Identification and experimental validation of KMO as a critical immune-associated mitochondrial gene in unstable atherosclerotic plaque.

Fu-Jun LiaoShao-Liang ShenHai-Long BaoHui LiQuan-Wei ZhaoLong ChenCai-Wei GongCheng-Zhu XiongWu-Peng LiuDanan Liu Da-Nan Liu

Published in: Journal of translational medicine (2024)

The results suggest that KMO, a mitochondria-targeted gene associated with macrophage cells, holds promise as a valuable diagnostic biomarker for assessing the instability of atherosclerotic plaques.

Keyphrases

induced apoptosis
copy number
genome wide
oxidative stress
cell cycle arrest
cell death
genome wide identification
coronary artery disease
adipose tissue
cancer therapy
big data
machine learning
reactive oxygen species
endoplasmic reticulum stress
pi k akt