MicroRNA-1252-5p Associated with Extracellular Vesicles Enhances Bortezomib Sensitivity in Multiple Myeloma Cells by Targeting Heparanase.

Dorival Mendes Rodrigues-JuniorMaria Fernanda de Andrade PelarinHelena Bonciani NaderAndré Luiz VettoreMaria Aparecida Silva Pinhal

Published in: OncoTargets and therapy (2021)

These results showed that miR-1252-5p could negatively regulate HPSE in MM, indicating the use of EVs carrying miR-1252-5p as a potential novel BTZ sensitization approach in MM cells.

Keyphrases

multiple myeloma
induced apoptosis
cell cycle arrest
cell death
oxidative stress
risk assessment
human health
cell proliferation
climate change