Elevated Uric Acid Mediates the Effect of Obesity on Hypertension Development: A Causal Mediation Analysis in a Prospective Longitudinal Study.

Conglin HongQiu ZhangYan ChenYing LuLinan ChenYan HeJing LiShengqi MaJun JiangXiaolong ZhangJianwei HuYi DingMingzhi ZhangHao Peng

Published in: Clinical epidemiology (2022)

Obesity preceded hyperuricemia and the latter partially mediated the relationship between obesity and hypertension, independent of behavioral and other metabolic factors.

Keyphrases

uric acid
metabolic syndrome
insulin resistance
weight loss
blood pressure
high fat diet induced
type diabetes
weight gain
adipose tissue
body mass index