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Pallidal versus subthalamic nucleus deep brain stimulation for levodopa-induced dyskinesia.

Shi-Ying FanKai-Liang WangWei HuRobert S EisingerAlexander HanChun-Lei HanQiao WangShimabukuro MichitomoJian-Guo ZhangFeng WangAdolfo Ramirez-ZamoraFan-Gang Meng
Published in: Annals of clinical and translational neurology (2019)
Both STN and GPi-DBS have a beneficial effect on LID but GPi-DBS provided greater anti-dyskinetic effects. Dyskinesia suppression for STN-DBS may depend on the reduction of levodopa equivalent dose. Unlike the STN, GPi-DBS might exert a direct and independent anti-dyskinesia effect.
Keyphrases
  • deep brain stimulation
  • parkinson disease
  • obsessive compulsive disorder
  • cerebral palsy
  • diabetic rats