Activation of STAT1 by the FRK tyrosine kinase is associated with human glioma growth.

Lei HuaGuanghui WangZhen WangJiale FuZhen FangTing ZhuangLiang ZhaoZhenkun ZongChengkun YeHongmei LiuYufu ZhuHengliang Shi

Published in: Journal of neuro-oncology (2019)

Our findings highlighted a critical role of FRK in tumor suppression ability through promoting STAT1 activation, and provided a potential therapeutic target for glioma.

Keyphrases

tyrosine kinase
epidermal growth factor receptor
endothelial cells
cell proliferation
induced pluripotent stem cells
human health
risk assessment