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Combinatorial conditioning of adipose derived-mesenchymal stem cells enhances their neurovascular potential: Implications for intervertebral disc degeneration.

Abbie L A BinchStephen M RichardsonJudith A HoylandFrank P Barry
Published in: JOR spine (2019)
This work highlights fundamental differences between the neurovascular secretome of donor-matched ASCs and MSCs, demonstrating the importance of cell-selection for tissue specific regeneration to reduce ectopic sensory nerve and blood vessel survival and improve patient outcomes.
Keyphrases
  • mesenchymal stem cells
  • umbilical cord
  • cell therapy
  • stem cells
  • single cell
  • bone marrow
  • peripheral nerve
  • human health
  • free survival
  • risk assessment