Mechanisms of Azole Resistance and Trailing in Candida tropicalis Bloodstream Isolates.

Pao-Yu ChenYu-Chung ChuangUn-In WuHsin-Yun SunJann-Tay WangWang-Huei ShengYee-Chun ChenShan-Chwen Chang

Published in: Journal of fungi (Basel, Switzerland) (2021)

Azole resistance and trailing are phenotypically and genotypically different in C. tropicalis. Interference with azole binding and MDR1 up-regulation confer azole resistance and trailing, respectively.

Keyphrases

candida albicans
biofilm formation
multidrug resistant
cystic fibrosis