A cross-sectional study on the association between Helicobacter pylori infection and headache.
Cinzia CavestroGiancarlo PrandiMatteo ManildoSabina MartiniCorrado GenovesiAlberto PremoliFlavio FraireLoris NeriSilvia MandrinoMarcella FerreroEugenia RotaPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2022)
Our study does not reveal an association between chronic HP infection and migraine. However, since HP is significantly associated with higher headache frequency, a role for HP as a risk factor for headache chronification, possibly underlain by inflammatory mechanisms, may be supposed.