Anti-Breast Cancer Effect of 2-Dodecyl-6-Methoxycyclohexa-2,5-Diene-1,4-Dione in vivo and in vitro Through MAPK Signaling Pathway.
Xing ZhouXingchun WuLuhui QinShunyu LuHongliang ZhangJinbin WeiLixiu ChenLuhui JiangYani WuChunxia ChenRenbin HuangPublished in: Drug design, development and therapy (2020)
Our study indicates that DMDD can inhibit proliferation, migration, and invasion and induces apoptosis and cell-cycle arrest of 4T1 breast cancer cells. Also, our findings indicate that DMDD induces the apoptosis of breast cancer cells and inhibits the growth in mice. Its mechanism may be related to the MAPK pathway.