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The dynamics of extracellular gadolinium-based contrast agent excretion into pleural and pericardial effusions quantified by T1 mapping cardiovascular magnetic resonance.

Simon ThalénMaren MaanjaAndreas SigfridssonEva MaretPeder SörenssonMartin Ugander
Published in: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance (2019)
T1 mapping shows that extracellular GBCA is excreted into pericardial and pleural effusions. Consequently, the previously used term vicarious excretion is misleading. Compared to pleural effusions, pericardial effusions had both a lower native T1, consistent with lesser relative fluid content in relation to other components such as proteins, and more prominent early excretion dynamics, which could be related to inflammation. The clinical diagnostic utility of T1 mapping to determine quantitative contrast dynamics in pericardial and pleural effusions merits further investigation.
Keyphrases
  • magnetic resonance
  • high resolution
  • contrast enhanced
  • high density
  • oxidative stress
  • preterm infants
  • magnetic resonance imaging
  • computed tomography
  • mass spectrometry
  • drug induced