Caffeine is associated with improved alveolarization and angiogenesis in male mice following hyperoxia induced lung injury.

Vikramaditya DumpaLori NielsenHuamei WangVasantha H S Kumar

Published in: BMC pulmonary medicine (2019)

Postnatal caffeine by modulating angiogenic gene expression early in lung development may restore the pulmonary microvasculature and alveolarization in adult lung.

Keyphrases

gene expression
high glucose
endothelial cells
dna methylation
pulmonary hypertension
preterm infants
diabetic rats
signaling pathway
drug induced
oxidative stress
wound healing