Acute radiation syndrome-related gene expression in irradiated peripheral blood cell populations.

Patrick OstheimAlan Don MallawaratchyThomas MüllerSimone SchüleCornelius HermannTanja PoppStefan EderStephanie Elisabeth CombsMatthias PortMichael Abend

Published in: International journal of radiation biology (2021)

T- and B-lymphocytes contributed predominantly to the radiation-induced up-regulation of FDXR/DDB2 and down-regulation of POU2AF1/WNT3. This study underlines the use of FDXR/DDB2 for biodosimetry purposes and POU2AF1/WNT3 for effect prediction of acute health effects.

Keyphrases

radiation induced
peripheral blood
liver failure
gene expression
respiratory failure
atrial fibrillation
cell proliferation
drug induced
stem cells
radiation therapy
aortic dissection
single cell
dna methylation
cell therapy
intensive care unit
case report
bone marrow
mechanical ventilation