Precise clinicopathologic findings for application of genetic testing in pediatric kidney transplant recipients with focal segmental glomerulosclerosis/steroid-resistant nephrotic syndrome.
Kenichiro MiuraNaoto KanekoTaeko HashimotoKiyonobu IshizukaYoko ShiraiMasataka HisanoHiroko ChikamotoYuko AkiokaShoichiro KandaYutaka HaritaToshiyuki YamamotoMotoshi HattoriPublished in: Pediatric nephrology (Berlin, Germany) (2022)
Our systematic approach based on precise clinicopathological findings including nephrotic syndrome, treatment responses, and diffuse foot process effacement might be useful to differentiate pediatric kidney transplant recipients with FSGS/SRNS who are likely to have a monogenic cause from patients who are not, and to predict post-transplant recurrence. A higher resolution version of the Graphical abstract is available as Supplementary information.