EBV load is associated with cfDNA fragmentation and renal damage in SLE patients.
Anna TruszewskaAgnieszka WirkowskaKamila GalaPiotr TruszewskiŁucja Krzemień-OjakKrzysztof MuchaLeszek PączekBartosz ForoncewiczPublished in: Lupus (2021)
We showed that EBV load was associated with non-uniform cfDNA fragmentation, higher cfDNA levels, and kidney disease in SLE patients. Although the causality of this relationship could not be determined with the current study, it brings rationale for further investigations on the role of EBV and cfDNA interplay in SLE pathogenesis.