Developing Biliary Atresia-like Model by Treating Human Liver Organoids with Polyinosinic:Polycytidylic Acid (Poly (I:C)).

Patrick Ho-Yu ChungRosana Ottakandathil BabuZhongluan WuKenneth Kak-Yuen WongPaul Kwong-Hang TamVincent Chi-Hang Lui

Published in: Current issues in molecular biology (2022)

Poly I:C treated human liver organoids exhibit morphology and genetic signature highly compatible to organoids developed from BA liver samples. They are potential research materials to study immune-mediated inflammation in BA.

Keyphrases

induced pluripotent stem cells
genome wide
dna methylation
climate change
newly diagnosed