C-Alkylation by Phenalenyl-Based Molecule via a Borrowing Hydrogen Pathway.

The present study demonstrates the first transition-metal-free catalytic C-alkylation via a borrowing hydrogen pathway for the α-alkylation of ketone, synthesis of substituted quinoline, and 9-monoalkylation of fluorene. With applications on diversification of biologically active molecules and gram-scale synthesis, a preliminary investigation of the reaction mechanism has been carried out, suggesting a radical-mediated borrowing hydrogen pathway.