Exploring the Mechanism of Action of Trachelospermi Caulis et Folium for Depression Based on Experiments: Combining Network Pharmacology and Molecular Docking.

Lingmiao Wen Yuqing Fan Wei Xiong Yanjun Liu Tinglan Zhang Guihua Wei Alvin Altamirano Tian-E Zhang Zhiyong Yan

Published in: Computational and mathematical methods in medicine (2022)

TCEF is a relatively safe antidepressant medicine that exerts therapeutic effects through multiple components, targets, and pathways, providing a new idea and theoretical basis for future use of TCEF to treat depression.

Keyphrases

molecular docking
depressive symptoms
molecular dynamics simulations
sleep quality
major depressive disorder
bipolar disorder