HLA-matched platelet transfusions are effective only in refractory patients with positive HLA antibody screening.
Aukje L KreugerAnja B U MäkelburgJudith A E SomersBert TomsonLeo M G van de WateringJohanna G van der BomMarian G J van KraaijClaudia M WellerPublished in: Transfusion (2019)
Matched platelet concentrates yielded maximal 1hCCIs, whereas mismatched transfusions still resulted in adequate increments. There is no indication for HLA-matched platelets in patients with negative antibody screens.