Cannabis use as a potential mediator between childhood adversity and first-episode psychosis: results from the EU-GEI case-control study.
Giulia TrottaVictoria RodriguezDiego QuattroneEdoardo SpinazzolaGiada TripoliCharlotte Gayer-AndersonTom P FreemanHannah E JongsmaLucia SideliMonica AasSimona A StiloCaterina La CasciaLaura FerraroDaniele La BarberaAntonio LasalviaSarah TosatoIlaria TarriconeGiuseppe D'AndreaAndrea TortelliFranck SchürhoffAndrei SzökeBaptiste PignonJean-Paul SeltenEva VelthorstLieuwe de HaanPierre-Michel LlorcaPaulo Rossi MenezesCristina M Del BenJose Luis SantosManuel ArrojoJulio BobesJulio SanjuánMiquel BernardoCelso ArangoJames B KirkbridePeter B JonesAlexander RichardsBart P RuttenJim Van OsIsabelle Austin-ZimmermanZhikun LiCraig MorganPak C ShamEvangelos VassosChloe WongRichard BentallHelen L FisherRobin M MurrayLuis AlamedaMarta Di Fortinull nullPublished in: Psychological medicine (2023)
Harmful patterns of cannabis use mediated the association between specific childhood adversities, like household discord, with later psychosis. Children exposed to particularly challenging environments in their household could benefit from psychosocial interventions aimed at preventing cannabis misuse.