Tetrabenazine, a vesicular monoamine transporter 2 inhibitor, inhibits vesicular storage capacity and release of monoamine transmitters in mouse brain tissue.

Pál Tod Anita Varga Viktor Román Balázs Lendvai Roland Pálkovács Beáta Sperlágh E Sylvester Vizi

Published in: British journal of pharmacology (2024)

Our observations provide neurochemical evidence explaining the mechanism of VMAT-2 inhibitors in the brain and support the involvement of dopaminergic and noradrenergic transmission in hyperkinetic movement disorders.

Keyphrases

resting state
white matter
functional connectivity
cerebral ischemia
brain injury
subarachnoid hemorrhage