Regression of Peritubular Capillaries Coincides with Angiogenesis and Renal Cyst Growth in Experimental Polycystic Kidney Disease.

Kristal O'BrienSaravanabavan Sayanthooran Jennifer Qin Jing ZhangAnnette T Y WongAlexandra MuntJane S BurgessGopala K Rangan

Published in: International journal of nephrology and renovascular disease (2020)

Regression of peritubular capillaries and disruption of vasa recta occur in parallel with angiogenesis and the progressive enlargement of kidney cysts. These data suggest that the regrowth of peritubular capillaries together with inhibition of angiogenesis are potential strategies to be considered in the treatment of PKD.

Keyphrases

polycystic kidney disease
endothelial cells
vascular endothelial growth factor
wound healing
multiple sclerosis
electronic health record
risk assessment
human health
climate change
deep learning
artificial intelligence
rare case