Heterozygous PAX6 mutations may lead to hyper-proinsulinaemia and glucose intolerance: A case-control study in families with congenital aniridia.

Wei TianXiao-Rong ZhuChun-Yan QiaoYing-Nan MaFang-Yuan YangZhen ZhouJian-Ping FengRan SunRong-Rong XieJing LuXi CaoJian-Bo ZhouJin-Kui Yang

Published in: Diabetic medicine : a journal of the British Diabetic Association (2020)

PAX6 may participate in the production of proinsulin to insulin and heterozygous PAX6 mutations may be associated with glucose metabolism in CA patients.

Keyphrases

end stage renal disease
early onset
ejection fraction
type diabetes
chronic kidney disease
newly diagnosed
insulin resistance