A study of somatic BRCA variants and their putative effect on protein properties in malignant mesothelioma.

Kritika KrishnamurthyKei Shing OhSarah AlghamdiVathany SriganeshanRobert Poppiti

Published in: Pleura and peritoneum (2023)

somatic variants were identified in 22% cases of malignant mesotheliomas in this study. The variants localize more frequently to the disordered regions of the protein and are predicted to affect the level of disorder.

Keyphrases

copy number
genome wide
protein protein
dna methylation
amino acid
binding protein
breast cancer risk