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Fragility Fractures: Risk Factors and Management in the Elderly.

Migliorini FilippoRiccardo GiorginoFrank HildebrandFilippo SpieziaGiuseppe Michele PerettiMario Alessandri-BonettiJörg EschweilerNikolaos Malliaropoulos
Published in: Medicina (Kaunas, Lithuania) (2021)
Given the progressive ageing of Western populations, the fragility fractures market has a growing socioeconomic impact. Fragility fractures are common in the elderly, negatively impacting their quality of life, limiting autonomy, increasing disability, and decreasing life expectancy. Different causes contribute to the development of a fractures in frail individuals. Among all, targeting fragile patients before the development of a fracture may represent the greatest challenge, and current diagnostic tools suffer from limitations. This study summarizes the current evidence on the management of fragility fractures, discussing risk factors, prevention, diagnosis, and actual limitations of the clinical therapeutic options, putting forward new ideas for further scientific investigation.
Keyphrases
  • risk factors
  • multiple sclerosis
  • end stage renal disease
  • middle aged
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • prognostic factors
  • south africa
  • health insurance
  • genetic diversity