Predicting Response to Chemotherapy in Patients With Newly Diagnosed High-Risk Neuroblastoma: A Report From the International Neuroblastoma Risk Group.
Anoop MayampurathSiddhi RameshDiana MichaelLiu LiuNicholas FeinbergMeaghan P GrangerArlene NaranjoSusan L CohnSamuel L VolchenboumMark A ApplebaumPublished in: JCO clinical cancer informatics (2022)
We demonstrate feasibility in using machine learning of diagnostic MIBG scans to predict response to induction chemotherapy for patients with high-risk neuroblastoma. We highlight improvements when clinical risk factors are also integrated, laying the foundation for using a multimodal approach to guiding treatment decisions for patients with high-risk neuroblastoma.