Is there evidence of potential overtreatment of glycaemia in elderly people with type 2 diabetes? Data from the GUIDANCE study.
Nicolle MüllerKamlesh KhuntiOliver KussUlf LindbladJohn J NolanGuy Ehm RuttenMarina TrentoMassimo PortaJohannes RothGuillaume CharpentierViktor JörgensUlrich A MüllerPublished in: Acta diabetologica (2016)
Most patients were treated according to guidelines valid at the time this large international patient sample was surveyed. Older and younger patients were at a similar level of metabolic control, and almost half of the patients with an age of ≥65 years and treated with insulin or sulfonylurea had HbA1c levels below the target range (≤7%) for younger patients. However, these patients have an increased risk of severe hypoglycaemic events with potentially dangerous complications, particularly in those with cardiovascular diseases.