Appetite-regulating hormone trajectories and relationships with fat mass development in term-born infants during the first 6 months of life.

Kirsten S de FluiterGerthe F KerkhofInge A L P van BeijsterveldtLaura M BreijLeonie C van Vark-van der ZeeMonique T MulderMarieke Abrahamse-BerkeveldAnita C S Hokken-Koelega

Published in: European journal of nutrition (2021)

Increasing ghrelin and decreasing PYY, thus increasing ghrelin/PYY ratio, suggests an increasing orexigenic drive until 6 months. ARH were different between BF and FF infants at 3 months, but did not correlate with human milk macronutrients. Ghrelin and leptin, but not PYY, correlated with more FM development during the first 6 months, suggesting that they might be involved in adiposity programming.

Keyphrases

human milk
low birth weight
preterm infants
depressive symptoms
gestational age
weight loss
type diabetes
body mass index
metabolic syndrome