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Association of metabolic syndrome and patatin-like phospholipase 3 - rs738409 gene variant in non-alcoholic fatty liver disease among a Chennai-based south Indian population.

Krishnasamy NarayanasamyRajendran KarthickPriyadarshini PanneerselvamNithya MohanArunkumar RamachandranRadhika PrakashMuthukumaran Rajaram
Published in: The journal of gene medicine (2020)
The PNPLA3 rs738409 gene polymorphism increases the risk of NAFLD by up to four-fold in subjects with an elevated level of triglyceride independent of other features of MetS.
Keyphrases
  • metabolic syndrome
  • insulin resistance
  • genome wide
  • copy number
  • liver fibrosis
  • type diabetes
  • genome wide identification
  • gene expression
  • dna methylation
  • skeletal muscle
  • genome wide analysis