The anxiolytic effect of salicylic acid is mediated via the GABAergic system in the fear potentiated plus maze behavior in rats.
Sahel MotaghiHadi Moghaddam Dizaj HerikGholamreza SepehriRazieh KooshkiSaeed Esmaeili-MahaniPublished in: Molecular biology reports (2021)
Our results showed that Salicylic acid has anxiolytic and hypnotic effects and it exerts its anxiolytic effect partly, via up the regulation of GAD1 in the ventral part of the hippocampus.