Contribution of neural crest and GLAST+ Wnt1+ bone marrow pericytes with liver fibrogenesis and/or regeneration.
Romina SierraSofía Gómez BustilloPolina KamenevaEsteban J FioreGraciela Lujan MazzoneMaximiliano BordaMaría V BlancoChiara UsuardiAlessandro FurlanPatrik ErnforsLaura D AlanizAlejandro D MontanerIgor AdameykoJorge Benjamin AquinoPublished in: Liver international : official journal of the International Association for the Study of the Liver (2020)
Our data suggest a gliosis process during liver fibrogenesis. While neural crest cells probably do not contribute with other liver cell types than glia, GLAST+ Wnt1-traced bone marrow pericytes are likely a source of endothelial and hepatocyte-like cells after liver injury and do not contribute to scarring.