Neurexin 3 Regulates Synaptic Connections Between Central Amygdala Neurons and Excitable Cells of the Lateral Parabrachial Nucleus in Rats with Varicella Zoster Induced Orofacial Pain.

Phillip R KramerRebecca S HornungMikhail UmorinM Douglas BensonPaul R Kinchington

Published in: Journal of pain research (2024)

The results suggest Nrxn3 reduces VZV associated orofacial pain, in part, by enhancing synaptic connections between GABA cells of the central amygdala and pain neurons within the lateral parabrachial nucleus.

Keyphrases

chronic pain
induced apoptosis
pain management
cell cycle arrest
prefrontal cortex
neuropathic pain
functional connectivity
minimally invasive
endoplasmic reticulum stress
cell death
oxidative stress
signaling pathway
high glucose
cell proliferation
stress induced