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Natural history of hearing and tumor growth in vestibular schwannoma in neurofibromatosis type 2-related schwannomatosis.

Takeshi WakabayashiRyota TamuraKosuke KaratsuMakoto HosoyaTakanori NishiyamaYasuhiro InoueKaoru OgawaJin KanzakiMasahiro TodaHiroyuki OzawaNaoki Oishi
Published in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2024)
Although the hearing preservation rate in NF2 cases is poor with the current treatment methods, many cases exist in which hearing acuity deteriorates, even during the natural course. Patients with an increased tumor volume during the follow-up period were more likely to experience hearing deterioration. Trial registration number 20140242 (date of registration: 27 October 2014).
Keyphrases
  • hearing loss
  • signaling pathway
  • clinical trial
  • oxidative stress
  • lps induced
  • immune response
  • phase ii
  • nuclear factor
  • toll like receptor