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GLP1R boosts survival, migration and invasion of endometrial cancer cells and protects against ferroptotic cell death.

Wu LiWen LyuSongjun LiuFan RuanXinmei Zhang
Published in: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology (2024)
In a word, GLP1R was up-regulated in EC and its up-regulation facilitated the proliferative and metastatic potentials, and protected cells from ferroptosis, thereby accelerating EC progression. These data emphasised the potency of GLP1R as a therapeutic agent against EC.
Keyphrases
  • cell death
  • squamous cell carcinoma
  • small cell lung cancer
  • cell cycle arrest
  • big data
  • endometrial cancer
  • free survival
  • deep learning