Blood loss reduction: effect of different knee prosthesis designs and use of tranexamic acid-a randomized controlled trial.

Use of the different prosthesis designs could significantly affect CBL and DV following TKA. However, the use of either design resulted in a comparable ANUBT. Regardless of prosthetic type, either IA- or IV-TXA could significantly reduce the CBL and ANUBT when compared to No-TXA.