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Value of 1-Hour Plasma Glucose During an Oral Glucose Tolerance Test in a Multiethnic Cohort of Obese Children and Adolescents.

Preneet Cheema BrarShilpa MehtaAjay BrarKristyn A PierceAlesandro AlbanoMichael Bergman
Published in: Clinical medicine insights. Endocrinology and diabetes (2023)
Our cross-sectional study affirms that the 1-hr PG can identify obese children and adolescents at increased risk for prediabetes and/or T2D with almost the same accuracy as a 2-hr PG. In our multi-ethnic cohort, a 1-hr PG ⩾ 155 mg/dL (8.6 mmol/l) serves as an optimal cut-point, using the estimation of the Youden index with AUC of 0.86 and sensitivity of 80%.We support the petition to consider the 1-hr PG as integral during an OGTT, as this adds value to the interpretation of the OGTT beyond the fasting and 2-hr PG.
Keyphrases
  • adipose tissue
  • metabolic syndrome
  • weight loss
  • type diabetes
  • blood pressure
  • insulin resistance
  • obese patients
  • skeletal muscle