Insights and Perspectives Regarding Nanostructured Fluorescent Materials toward Tackling COVID-19 and Future Pandemics.
Mohit SarafMohammad Tavakkoli Yarakinull PrateekYen Nee TanRaju Kumar GuptaPublished in: ACS applied nano materials (2021)
The COVID-19 outbreak has exposed the world's preparation to fight against unknown/unexplored infectious and life-threatening pathogens. The unavailability of vaccines, slow or sometimes unreliable real-time virus/bacteria detection techniques, insufficient personal protective equipment (PPE), and a shortage of ventilators and many other transportation equipments have further raised serious concerns. Material research has been playing a pivotal role in developing antimicrobial agents for water treatment and photodynamic therapy, fast and ultrasensitive biosensors for virus/biomarkers detection, as well as for relevant biomedical and environmental applications. It has been noticed that these research efforts nowadays primarily focus on the nanomaterials-based platforms owing to their simplicity, reliability, and feasibility. In particular, nanostructured fluorescent materials have shown key potential due to their fascinating optical and unique properties at the nanoscale to combat against a COVID-19 kind of pandemic. Keeping these points in mind, this review attempts to give a perspective on the four key fluorescent materials of different families, including carbon dots, metal nanoclusters, aggregation-induced-emission luminogens, and MXenes, which possess great potential for the development of ultrasensitive biosensors and infective antimicrobial agents to fight against various infections/diseases. Particular emphasis has been given to the biomedical and environmental applications that are linked directly or indirectly to the efforts in combating COVID-19 pandemics. This review also aims to raise the awareness of researchers and scientists across the world to utilize such powerful materials in tackling similar pandemics in future.
Keyphrases
- label free
- coronavirus disease
- sars cov
- quantum dots
- photodynamic therapy
- human health
- staphylococcus aureus
- respiratory syndrome coronavirus
- current status
- risk assessment
- living cells
- quality improvement
- high resolution
- molecularly imprinted
- high speed
- climate change
- life cycle
- antimicrobial resistance
- atomic force microscopy
- fluorescent probe
- smoking cessation
- mass spectrometry
- loop mediated isothermal amplification