Age and APOE genotype affect the relationship between objectively measured physical activity and power in the alpha band, a marker of brain disease.

Jaisalmer de Frutos-LucasPablo CuestaFederico Ramírez-TorañoAlberto NebredaEsther Cuadrado-SotoÁfrica Peral-SuárezDavid Lopez-SanzRicardo BruñaSilvia Marcos-de PedroMaría Luisa Delgado-LosadaAna María López-SobalerInmaculada Concepción Rodríguez-RojoAna BarabashJuan Manuel Serrano RodriguezSimon M LawsAlberto Marcos DoladoRamón López-HigesBelinda M BrownFernando Maestú

Published in: Alzheimer's research & therapy (2020)

PA could protect against the slowing of brain activity that characterizes the AD continuum, where it is of benefit for all individuals, especially E3/E4 older adults.

Keyphrases

physical activity
resting state
white matter
cognitive decline
body mass index
high fat diet
sleep quality
functional connectivity
metabolic syndrome
multiple sclerosis
depressive symptoms
mild cognitive impairment
skeletal muscle