Association of rare, recurrent nonsynonymous variants in the germline of prostate cancer patients of African ancestry.

Jun WeiJennifer Beebe-DimmerZhuqing ShiChristopher SampleGuifang YanAndrew S RifkinAzita SadeghpourMarta GielzakSodam ChoiDavid MoonS Lilly ZhengBrian T HelfandPatrick C WalshJianfeng XuKathleen A CooneyWilliam B Isaacs

Published in: The Prostate (2022)

This WES study identified two rare, recurrent nonsynonymous PCa risk-associated variants in AA. Confirmation in additional large populations of AA PCa cases and controls is required.

Keyphrases

copy number
prostate cancer
dna repair
gene expression
oxidative stress
genome wide