A History of Suicide Attempt Is Associated with Increased Sympathetic Activation in Bipolar Disorder.

Abigail OrtizYunkyung ParkStephane MacLeanMuhammad Ishrat HusainMarcos SanchesArun V RavindranBenoit H Mulsant

Published in: Canadian journal of psychiatry. Revue canadienne de psychiatrie (2023)

Our results suggest that changes in the ANS in patients with BD and a history of suicide attempt are not restricted to pure vagally mediated HRV parameters, but rather signal a general ANS dysregulation. This ANS imbalance may be contributing to illness burden and cardiovascular disease. Further research on the relationship between ANS and suicidality in BD is needed.

Keyphrases

bipolar disorder
cardiovascular disease
major depressive disorder
type diabetes
risk factors
coronary artery disease
metabolic syndrome