Quxie Capsule Modulating Gut Microbiome and Its Association With T cell Regulation in Patients With Metastatic Colorectal Cancer: Result From a Randomized Controlled Clinical Trial.

Ling-Yun SunYunzi YanDongmei ChenYufei Yang

Published in: Integrative cancer therapies (2021)

QX capsule could enhance TH cells level among mCRC patients and increase the abundance of gut anticancer bacteria such as Actinobacteria as well as butyrate-producing bacteria such as Lachnospiraceae. These results indicated that QX capsule might have the property of dual effects of antitumor and immunity enhancement, both mediated by the microbiome.

Keyphrases

metastatic colorectal cancer
end stage renal disease
induced apoptosis
ejection fraction
newly diagnosed
prognostic factors
cell cycle arrest
signaling pathway
oxidative stress
cell proliferation
cell death
endoplasmic reticulum stress
patient reported