Distinctive alterations in the mesocorticolimbic circuits in various psychiatric disorders.
Yuko NakamuraTakuya IshidaSaori C TanakaYuki MitsuyamaSatoshi YokoyamaHotaka ShinzatoEri ItaiGo OkadaYuko KobayashiTakahiko KawashimaJun MiyataYujiro YoshiharaHidehiko TakahashiRyuta AokiMotoaki NakamuraHaruhisa OtaTakashi ItahashiSusumu MoritaShintaro KawakamiOsamu AbeNaohiro OkadaAkira KunimatsuAyumu YamashitaOkito YamashitaHiroshi ImamizuJun MorimotoYasumasa OkamotoToshiya MuraiRyu-Ichiro HashimotoKiyoto KasaiMitsuo KawatoShinsuke KoikePublished in: Psychiatry and clinical neurosciences (2023)
Impaired signaling in the mesocorticolimbic dopamine-related circuits could be an underlying neuropathogenesis of various psychiatric disorders. These findings will improve the understanding of unique neural alternations of each disorder and will facilitate identification of effective therapeutic targets. This article is protected by copyright. All rights reserved.