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Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate NHB17965 from a HBV infected patient.

Modhusudon ShahaPalash Kumar SarkerMd Saddam HossainKeshob Chandra DasMunira JahanShuvra Kanti DeyShahina TabassumAbu HashemMd Salimullah
Published in: F1000Research (2018)
The burden of chronic hepatitis B virus (HBV) infections is increasingly detected nowadays. Herein, we report a complete genome of HBV subgenotype C2 (HBV/C2) from a HBV infected patient. Complete genome analysis revealed that the isolated strain was a non-recombinant wild type and had several regular substitutions in the reverse transcriptase domain and small surface proteins of HBV. This study may help clinicians and scientists gain in-depth knowledge on the current substitutions of HBV/C2 genome and to identify potential therapies against HBV infections.
Keyphrases
  • hepatitis b virus
  • liver failure
  • healthcare
  • genome wide
  • case report
  • wild type
  • palliative care
  • drug induced