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Effect of black cloth ointment on hypertrophic scar formation: An investigation using integrated network pharmacology and animal assay.

Qin GuoJin JiFang ChenJianxin ShiHuaxu LiuChangle Zhu
Published in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2024)
Our findings indicate that the material basis for the scar-improving effects of the BCO is β-elemene, and cellular apoptosis is the key mechanism through which the BCO and β-elemene exert their effects.
Keyphrases
  • oxidative stress
  • wound healing
  • endoplasmic reticulum stress
  • cell death
  • cell cycle arrest