Cell-free DNA test for fetal chromosomal abnormalities in multiple pregnancies.

Angel Hoi Wan Kwan María Del Mar GilShuwen XueYvonne K Y KwokDoris LauJoanna FungAndrea ChanKwong-Wai Choy Tak Yeung LeungLiona C Poon

Published in: Acta obstetricia et gynecologica Scandinavica (2024)

cfDNA testing in twin pregnancies has sufficient screening performance for trisomy 21 but the number of affected cases for other conditions is limited to draw any meaningful conclusion. The use of cfDNA testing in triplet pregnancies and vanishing twins remains an area for further research.

Keyphrases

gestational age
preterm birth
pregnancy outcomes
gene expression
pregnant women
copy number
genome wide