Nonstationary coupling between heart rate and perfusion index in extremely preterm infants in the first day of life.
John M O'TooleEugene M DempseyDavid Van LaerePublished in: Physiological measurement (2021)
Nonstationary features are necessary to distinguish different coupling types for complex biomedical systems. Time-varying directional coupling between PI and HR provides objective and independent biomarkers of adverse outcome in extremely preterm infants.