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Bone morphogenetic protein in subaxial cervical arthrodesis: a meta-analysis of 5828 patients.

Sufyan IbrahimGiorgos D MichalopoulosPatrick FlaniganSarah E JohnsonKonstantinos KatsosArjun S SebastianBrett A FreedmanMohamad Bydon
Published in: Journal of neurosurgery. Spine (2024)
Use of BMP in ACDF offers higher rates of augmented fusion and lower rates of all-cause reoperation but with an increased risk of dysphagia. The benefit of fusion outweighs the risk of dysphagia with a higher BMP dose in older patients being operated on for < 2 levels. The use of BMP in PCF seems to have a less important effect on clinical and radiological outcomes.
Keyphrases
  • mesenchymal stem cells
  • bone regeneration
  • bone marrow
  • insulin resistance