Leveraging the Treg-intrinsic CTLA4-PKCη signaling pathway for cancer immunotherapy.

Hsin-Yu LiuChristophe PedrosKok-Fai KongAnn J Canonigo-BalancioWen XueAmnon Altman

Published in: Journal for immunotherapy of cancer (2022)

These findings demonstrate the potential utility of PKCη inhibition as a viable clinical approach to treat patients with cancer, especially when combined with adjuvant therapies.

Keyphrases

signaling pathway
early stage
pi k akt
protein kinase
human health
cell proliferation