The pandemic of the coronavirus infection Covid-19, which spread around the world in 2020, changed the lives of millions of people and negatively affected the life and functioning conditions of all countries, people and nations without exception. With the emergence of the opportunity to be vaccinated against Covid-19, the problem of making a decision about vaccination also appeared. But recently, it has become increasingly clear that the coronavirus disease in the world is moving into the group of annual viral epidemic diseases that occur every year in different countries during the seasonal wave of acute respiratory viral infections. The ongoing Covid-19 pandemic against the background of the adoption of serious quarantine measures indicates the need for large-scale vaccination of the population as the most effective way to protect against Covid-19. In this article, we pay special attention to vaccination, as the main factor in ensuring health, reducing the morbidity and severity of the course of the Covid-19 disease, and an important task of the state and modern public administration. Plans regarding vaccination, under the conditions of the war in Ukraine, will not be implemented in full - this all the more requires attention to this issue.