Lower Prevalence of Osteoporosis in Patients with COPD Taking Anti-Inflammatory Compounds for the Treatment of Diabetes: Results from COSYCONET.
Kathrin KahnertRudolf A JoerresTanja LuckeFranziska C TrudzinskiPontus MertschChristiane BickertJoachim H FickerJürgen BehrRobert BalsHenrik WatzTobias WelteClaus F VogelmeierPeter Alternull nullPublished in: International journal of chronic obstructive pulmonary disease (2021)
In a large COPD cohort, anti-inflammatory diabetes therapy, including metformin, was associated with a lower prevalence of osteoporosis, especially in patients with higher symptoms and exacerbations. These findings suggest a protective effect of common anti-diabetic medication on osteoporosis, possibly as a result of attenuated systemic inflammation.
Keyphrases
- anti inflammatory
- chronic obstructive pulmonary disease
- postmenopausal women
- type diabetes
- bone mineral density
- cardiovascular disease
- risk factors
- lung function
- glycemic control
- cystic fibrosis
- healthcare
- body composition
- insulin resistance
- sleep quality
- bone marrow
- wound healing
- replacement therapy
- physical activity
- mesenchymal stem cells
- electronic health record