The relationship between PNP, GSTO-1, AS3MT and ADRB3 gene polymorphisms and urinary arsenic concentration among copper smelter and refinery employers.

A Szymańska-ChabowskaT MatysŁ ŁaczmańskiK CzerwińskaA JanusB SmykG MazurR PorębaPawel Gac

Published in: Human & experimental toxicology (2020)

This study indicates that arsenic absorption and metabolism depend on polymorphisms of genes encoding PNP and GSTO-1. Individuals with disadvantageous constellation of polymorphisms are more susceptible to harmful effects of arsenic exposure.

Keyphrases

drinking water
heavy metals
genome wide
gene expression
dna methylation